The hearing theory announced in the first half of the 20th century by Georg von Bekesy requires reviewing and updating. There has been a huge advancement in the sciences ever since, which allows to deepen the understanding of processes responsible for reception, processing and transmission of acoustic information. The study paid attention to several issues related to hearing...

A preliminary analysis of B.1.1.529 indicates it contains multiple spike protein mutations and is highly infectious [2]. As opposed to other variants of concern (VOC), preliminary evidence indicates that this variant has a higher risk of reinfection. Nearly all provinces in South Africa are experiencing an increase in this variant. Omicron is the name of the variant (B.1.1.529)...
National Early Warning Score (NEWS) 2 was developed by the Royal College of Physicians to be used as early detection of in-hospital patient deterioration. The score has been shown to improve prognosis and triage efficiency. While the benefit of using a triage system has been established, in the real world, inefficient manual data entry and human error contribute to possible delays in identifying patients requiring intensive care transfers...
Nutrition of under-five children is very critical because the basis of life time health strength and brain development is laid during this period. To assess the feeding practices and its effect on the nutritional status of HIV-infected under- five children in Southeast Nigeria....
The solution of the AP problem directly depends on its concept, which sets the direction of research and development. The system of dominant views on the nature and mechanisms of AP development today does not agree with a number of fundamental foundations of medical science and the facts of real reality. The analysis of the 5 most common misconceptions, which are separate....
Worldwide, Brucellosis remains a major zoonosis. This disease remains a major problem among animals and humans too gets infected through unpasteurized milk or handling products of cattles. Herein we are discussing a case who presented with complaints of fever for one month, shock and leukemoid reaction was found to have brucellosis and responded well with gentamycin and doxycycline.....
It is not known how patients who receive a secondary prevention Implantable Cardioverter Defibrillator (ICD) in clinical practice compare with patients from the Antiarrhythmic Versus Implantable Defibrillator (AVID) trial. We compared the characteristics of patients in the AVID trial with those receiving a secondary prevention ICD in the National Cardiovascular Data Registry (NCDR) ICD Registry. We included all randomized AVID patients and patients in the ICD Registry undergoing first-time secondary prevention ICD implantation (2006-2008)....
Smartphones are items of great handling during the hospital workday. Biosafety is compromised by its use, since they come into frequent contact with the hands of professionals. Often, they are left on surfaces of different sectors in the same day, being able to transfer microorganisms. The hypothesis formulated for the work was that the evaluation of the microbiota found in the culture...
Cardiovascular Diseases Associated Inflammatory Biomarker Levels in A Small Cohort of HIV-1 Infected Patients Deintensificated from Abacavir/Lamivudine/ Dolutegravir to Lamivudine Plus Dolutegravir
Following the successful introduction of combined antiretroviral therapy (cART), a dramatic decrease in viral burden and opportunistic infections along with a consistent increase in life expectancy has been observed in human immunodeficiency virus (HIV) infected patients [1]. This deep change in the HIV disease evolution has determined that HIV positive subjects were effectively monitored for several alterations of many tissue and organs...
An Unusual Case of High-Grade B-Cell Lymphoma with Both C-Myc and Ccnd1 Rearrangement- “Double-Hit” Lymphoma (Nmrr-18-481-40980)
The 2016 revision of the World Health Organization (WHO) classification for lymphoma has included a new category of lymphoma, separate from diffuse large B-cell lymphoma, termed high-grade B-cell lymphoma with translocations involving myc and bcl-2 or bcl- 6. These lymphomas, which occur in <10% of cases of diffuse large B-cell lymphoma, have been referred to as double-hit....
Kaposi sarcoma was one of the signals of the start of the AIDS Epidemic in 1981, and since the beginning it was a source of stigma and discrimination; patients were pushed to social segregation due to the deleterious physical consequences of KS. Myiasis on the other side is a sign of poverty and deprivation of care....
Cholecystitis Xanthogranulomatous Clinical Pathological an Analysis of 20 Cases
The XGC is a rare variant of chronic cholecystitis, is considered a non-neoplastic reactive process, however, is an entity that confuses macroscopically and image for gallbladder cancer. It is characterized by the presence of chronic inflammatory infiltration, granuloma formation with fibrosis, histiocytic reaction with foamy macrophages...
The Superficial Venous System: Art and Anatomy in Michelangelo’s Works
The Renaissance period was a laboratory of extensive scientific and artistic production that also included the study of the human body for both medical and artistic purpose. The artists of this period, especially those of the Italian schools, were particularly fascinated by human dissection and began to attend or perform public human dissections or public lessons of anatomy...
Over the last decades more than 100 infectious agents emerged or reemerged, bringing numerous epidemic outbreaks and three pan- demics with a high cost in human lives and economical losses. This phenomen is not new, and has its origin in the environmental, social, climatic, and behavioral changes resulting from the human demo- graphic explosion which currently exceeds....
Therapeutic Potential of Paclitaxel Against COVID-19: A Short Communication
COVID-19: Coronavirus disease-2019; SARS-CoV-2: Severe acute respiratory syndrome coronavirus 2; MAPK: Mitogen-activated protein kinase; NF-κB: Nuclear factor-κB; IL-1β: Interleukin-1β; TNFα: Tumor necrosis factor α; TGFβ: Transforming growth factor β; IFN-γ: Interferon γ; JAK: Janus kinase; STAT: Signal transducer....
Geographically Weighted Regression Modelling of the Spatial Association Between Malaria Cases and Environmental Factors in Cameroon
Studies have illustrated the association of ma- laria cases with environmental factors in Cameroon but limited in addressing how these factors vary in space for timely public health interventions. Thus, we want to find the spatial variability between malaria hotspot cases and environmental predictors using Geograph- ically weighted regression (GWR) spatial modelling technique....
Cancer Moon Shot – Launch Your Patent Application Before it is too Late!
Andre Gide once said, “One doesn't discover new lands without consenting to lose sight of the shore for a very long time.” The journey every single inventor makes through the patenting process is admittedly uncertain, with no assurances that it will result in an issued patent. But a terrific program implemented by the United States Patent and Trademark Office (USPTO) makes such a journey far shorter than...
Global Prevalence of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis
Evidence suggests that diabetes in all forms are on the rise especially gesta- tional diabetes mellitus which increases the risk of maternal and neonatal morbidities; however global prevalence rates and geographical distribution of GDM remain uncertain. The aim of this study is to examine the global burden of gestational diabetes mellitus...
With the spread of the new coronavirus around the world, governments of various countries have begun to use the mathematical modelling method to construct some virus transmission models assessing the risks of spatial spread of the new coronavirus COVID-19, while carrying out epidemic prevention work...
Nebulized Therapy with Plasma-Platelet Growth Factors in Control of Cytokin Storm Hyperinmune Phenomenon in Lungs of Patients Affected by COVID-19
In Regenerative Medicine, application of Plasma Growth Factors (PRP) represents a great scientific advance that opens a new knowledge in the functioning of platelets and their function on the im- mune system, intervening not only in bactericidal processes, but in complex mechanisms to regulate processes related to inflammation and cellular immunity through a large number of cytokines and interleukins (3, 4)....
Ischemic Heart Disease and Psychiatric Comorbidities: A Preliminary Local Survey
Psychosocial stresses and psychiatric problems may make worse the prognosis of patients with ischemic heart disease. Therefore, assessing their incidence among this group of patients may perhaps enhance our perception concerning their dynamic significance in the ground of psychological medicine....
The author developed his GH-Method: Math-Physical Medicine (MPM) by apply- ing mathematics, physics, engineering modeling, and computer science (big data analytics and AI) to derive the mathematical metabolism model and three predic- tion tools for weight, FPG, and PPG with >30 input elements. This study includes 11 categories: weight, glucose, blood...
Using Candlestick Charting and GH-Method: Math-Physical Medicine to Investigate the Differences of Glucose Measurement Results Based on Both Finger-Piercing Method and Continuous Monitoring Device
The author developed his GH-Method: Math-Physical Medicine (MPM) by applying mathematics, physics, engineering modelling, and computer science such as big data analytics and artificial intelligence to derive the mathematical metabolism model and three prediction tools for weight, FPG, and PPG with >30 input elements. This research paper...
Ectopic Pregnancy (EP), defined as implantation of the blastocyte outside the endometrial cavity, is preva- lent in 2% of pregnancies [1]. Abdominal bleeding from ruptured EP is the leading cause of maternal death in the first trimester, accounts for 6% of all maternal deaths [2]. Major risk factors include a history of tubal surgery, former pelvic inflammatory disease, assisted...
We present the observation of a young woman of 30 years whose discovery of the teratoma was fortuitous, aided by pelvic computed tomography, the diagnosis of benign teratoma is confirmed by the anatomopathological study of the operative part. The puncture and the biopsy are contraindicated due to infectious risk, fistula, and neoplastic dissemination...
Female Athletic Syndrome is a triad of medical condition that is frequently seen in physically active young women characterized by disordered eating, amenorrhea and osteoporosis. It can be summed up as low energy availability, menstrual dysfunction and low bone density. In India where female nutrition is inappropriate, inadequate and often unhealthy, with...
In order to meet the growing needs of the European Union medicinal and aromatic plants, Hungary is still one of the major exporters today, although earlier, until the 1980s, we were considered a great herb-growing nation. Therefore, the development of the national medicinal and aromatic herb growing sector is an essential requirement for maintaining and developing our market position....
The learning disabilities are the neurological problem, in which one or more basic psychological processes are disturbed, which are involved in understanding. There are 5 categories of learning disabilities i.e. dyslexia, dysgraphia, dyscalculia, auditory processing disorder, language processing disorder, nonverbal learning disabilities. The major causes of...
The Third Case of the Extended Michelin Tire Baby Syndrome Associated with Undescended Testis, Mental Retardation and Hearing Impairment
Michelin tire baby syndrome is a very rare heterogeneous disorder, characterized by congenital generalized circumferential folding of excess skin occurring as an isolated abnormality or in association with various phenotypic abnormalities....
A 45 year old female with kidney failure due to Alport Syndrome (hereditary nephritis) underwent a deceased-donor kidney transplant. Immune suppression consisted of tacrolimus, sirolimus and prednisolone. Initial graft function was excellent (serum creatinine concentration 1.25 mg/dl), but...
The study included 155 subjects (155 eyes), age ranged from 18 to 27 years. All subjects underwent full ophthalmological examination in ophthalmology department of a tertiary care hospital including: 1. Measurement of spherical equivalent (SE) using Auto Refractometer. 2. Visual acuity using Snellen chart. 3. Anterior segment examination using slit lamp...
Based on a prospective study that included a total of 79 subjects (≥32 gestational weeks) with VAS score of ≥ 5 were randomly divided into a control group (n = 21) and three treatment groups [exercise (n = 19); acetaminophen...
Prophylaxis and Risk Factors for Venous Thromboembolism (VTE): Knowledge and Practice of Surgeons
Venous thromboembolism (VTE) is one of the most common medical problems with its most common complication pulmonary embolism (PE).The aim of this study is to assess the knowledge and attitude of a surgeon regarding VTE risk factors and prophylaxis...
An Uncommon Chest Pain in a 26-Year-Old Woman: Anoma-lous Origin of Left Coronary Artery from the Pulmonary Artery
A 26-year-old woman reported a history longer than 2 months of precordial pain, exertional chest tightness and shortness of breath. Her past medical history was remarkable for remote endocardial fibroelastosis and permanent atrial fibrillation. A grade 2/6 systolic murmur was heard at the cardiac apex. Her serial cardiac enzyme results were negative. Electrocardiographic examination showed left ventricular hypertrophy...
Cystic Mass of the Hepatic Hilar Region in a 16-Year-Old Girl: Hepatic Infarction
A previously healthy 16-year-old girl was referred for further evaluation of intermittent epigastric pain and distention for one week. During this episode, she occasionally suffered high fever up to 38°C. Her review of systems was unremarkable, and no abdominal mass was detected on palpation...
Honokiol (HNK) is a biphenolic compound derived from the bark of magnolia officinalis. Over the past decades, HNK is frequently prescribed as a pharmaceutical ingredient for inflammatory disease, which is s a complex pathological process closely related to oxidative stress and immune response...